MECP2 抗体 (pSer421)
Quick Overview for MECP2 抗体 (pSer421) (ABIN6254071)
抗原
See all MECP2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer421
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特异性
- Specific for endogenous levels of the ~55 kDa truncated MeCP2 protein phosphorylated at Ser421. Immunolabeling is blocked by preadsorption with the phosphopeptide used as antigen, but not by the corresponding non-phosphopeptide.
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交叉反应
- 小鼠, 大鼠
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预测反应
- human, non-human primate
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产品特性
- Our MeCP2 (Ser421) rabbit polyclonal phosphospecific primary antibody is produced in-house. It detects MeCP2 (Ser421) and is antigen affinity purified from pooled serum. It is great for use in ELISA, WB.
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纯化方法
- Prepared from pooled rabbit serum by affinity purification via sequential chromatography on phospho and non-phosphopeptide affinity columns.
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免疫原
- Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser421 of mouse MeCP2, conjugated to keyhole limpet hemocyanin (KLH).
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亚型
- IgG
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应用备注
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Dilution Range: WB Brain: 1:1000
Dilution Range: WB: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg per ml BSA and 50 % glycerol.
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储存条件
- -20 °C
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储存方法
- Storage at -20°C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at -20°C.
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有效期
- 12 months
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: "Developmental nicotine exposure engenders intergenerational downregulation and aberrant posttranslational modification of cardinal epigenetic factors in the frontal cortices, striata, and hippocampi ..." in: Epigenetics & chromatin, Vol. 13, Issue 1, pp. 13, (2020) (PubMed).
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: "Developmental nicotine exposure engenders intergenerational downregulation and aberrant posttranslational modification of cardinal epigenetic factors in the frontal cortices, striata, and hippocampi ..." in: Epigenetics & chromatin, Vol. 13, Issue 1, pp. 13, (2020) (PubMed).
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- MECP2 (Methyl CpG Binding Protein 2 (MECP2))
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别名
- MECP2
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背景
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Synonyms: AUTSX 3 antibody, AUTSX3 antibody, DKFZp686A24160 antibody, Mbd 5 antibody, Mbd5 antibody, MECP 2 antibody, MeCP 2 protein antibody, MeCP-2 protein antibody, Mecp2 antibody, MECP2_HUMAN antibody, Methyl CpG binding protein 2 (Rett syndrome) antibody, Methyl CpG binding protein 2 antibody, Methyl-CpG-binding protein 2 antibody, MRX 16 antibody, MRX 79 antibody, MRX16 antibody, MRX79 antibody, MRXS 13 antibody, MRXS13 antibody, MRXSL antibody, PPMX antibody, RS antibody, RTS antibody, RTT antibody, WBP 10 antibody, WBP10 antibody
Description Logic: Our MeCP2 (Ser421) rabbit polyclonal phosphospecific primary antibody is produced . It detects MeCP2 (Ser421) and is antigen affinity purified from pooled serum. It is great for use in ELISA, WB.
Gene Name Alternatives: MECP2
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分子量
- 55 kDa
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基因ID
- 17257
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UniProt
- Q9Z2D6
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途径
- Inositol Metabolic Process, Chromatin Binding, Synaptic Membrane
抗原
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